|
rs189660050
|
|
|
0.010 |
GeneticVariation |
BEFREE |
ZPBP2 p.T69I was at the non-conserved region and was predicted to be benign by in silico analysis, whereas GPATCH8 p.A979P was at a highly conserved region and was predicted to be deleterious, which made p.A979P a conceivable candidate for juvenile-onset hyperuricemia.
|
21594610 |
2011 |
|
rs35258188
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
Identification of CDC42BPG as a novel susceptibility locus for hyperuricemia in a Japanese population.
|
29124443 |
2018 |
|
rs138551969
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
Identification of CDC42BPG as a novel susceptibility locus for hyperuricemia in a Japanese population.
|
29124443 |
2018 |
|
rs143583842
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
Identification of CDC42BPG as a novel susceptibility locus for hyperuricemia in a Japanese population.
|
29124443 |
2018 |
|
rs28934583
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We describe here a novel heterozygous mutation of <i>UMOD</i> (c.249C>G; p.Cys83Trp) in an affected 9-year-old boy with progressive renal impairment and hyperuricemia.
|
29424336 |
2019 |
|
rs660339
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The haplotype A-T (-866G/A-Ala55Val) was a protective factor for hyperuricemia in the female subgroup (OR = 0.80, P = 0.017).
|
27273589 |
2016 |
|
rs151305324
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
Identification of CDC42BPG as a novel susceptibility locus for hyperuricemia in a Japanese population.
|
29124443 |
2018 |
|
rs130154
|
|
|
0.010 |
GeneticVariation |
BEFREE |
For the Uygur population, IL-8 rs4073, IL-18 rs187238 and IL-18RAP rs130154 polymorphisms were all associated with hyperuricemia (P<0.001 by genotype and P=0.008, OR 0.802 by allele for IL-8; P=0.01 by genotype and P=0.006, OR 1.332 by allele for IL-18 rs187238; P=0.007 by genotype and P=0.005, OR 1.27 by allele for IL-18RAP rs130154).
|
26722554 |
2015 |
|
rs149454410
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
Identification of CDC42BPG as a novel susceptibility locus for hyperuricemia in a Japanese population.
|
29124443 |
2018 |
|
rs16890979
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Three SNPs, URAT1 rs11231825, GLUT9 rs16890979 and ABCG2 rs2231142, previously associated in our population with hyperuricemia and gout, were analyzed in 27 patients with HPRT deficiency treated with allopurinol for at least 5 years.
|
29879316 |
2018 |
|
rs6855911
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The polymorphism rs6855911 in SLC2A9 may be a genetic marker to assess risk of hyperuricemia among Chinese male Han population.
|
20972595 |
2011 |
|
rs33972313
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We measured plasma urate and genotyped for the SLC23A1 rs33972313 vitamin C variant in 106 147 individuals from the Copenhagen General Population Study, of which 24 099 had hyperuricaemia.
|
29939348 |
2018 |
|
rs149722479
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
Identification of CDC42BPG as a novel susceptibility locus for hyperuricemia in a Japanese population.
|
29124443 |
2018 |
|
rs3825016
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The correlation between rs3825016 polymorphism of SLC22A12 and hyperuricaemia susceptibility is possible.
|
29352852 |
2018 |
|
rs3825016
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The frequency of rs3825016 (C/T) CT genotype was significant higher in the hypertensive patients with hyperuricemia than that in the healthy controls (32.7 vs 18.8%; p = 0.02).
|
26086348 |
2015 |
|
rs11231825
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Three SNPs, URAT1 rs11231825, GLUT9 rs16890979 and ABCG2 rs2231142, previously associated in our population with hyperuricemia and gout, were analyzed in 27 patients with HPRT deficiency treated with allopurinol for at least 5 years.
|
29879316 |
2018 |
|
rs11602903
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The strongest association with hyperuricaemia was observed for rs75786299 (IVS3+11A/G) with an OR of 32.05. rs7929627 (IVS7-103A/G) and rs3825017 (N82N) showed an association with hyperuricaemia with ORs of 2.56 and 2.29, respectively. rs11602903 (788A/T) and rs121907892 (W258X) were negatively correlated with hyperuricaemia with ORs of 0.350 and 0.447, respectively.
|
26603249 |
2015 |
|
rs121907892
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The strongest association with hyperuricaemia was observed for rs75786299 (IVS3+11A/G) with an OR of 32.05. rs7929627 (IVS7-103A/G) and rs3825017 (N82N) showed an association with hyperuricaemia with ORs of 2.56 and 2.29, respectively. rs11602903 (788A/T) and rs121907892 (W258X) were negatively correlated with hyperuricaemia with ORs of 0.350 and 0.447, respectively.
|
26603249 |
2015 |
|
rs1230053514
|
|
|
0.010 |
GeneticVariation |
BEFREE |
ZPBP2 p.T69I was at the non-conserved region and was predicted to be benign by in silico analysis, whereas GPATCH8 p.A979P was at a highly conserved region and was predicted to be deleterious, which made p.A979P a conceivable candidate for juvenile-onset hyperuricemia.
|
21594610 |
2011 |
|
rs1529909
|
|
|
0.010 |
GeneticVariation |
BEFREE |
101 hypertensive patients with hyperuricemia were detected the genotypes of URAT1 rs1529909 and rs3825016 and undergo a 2-weeks following losartan treatment.
|
26086348 |
2015 |
|
rs3825017
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Individuals carrying the GATAG haplotype (n=32)-a relatively common variant consisting of rs7929627, rs75786299 and rs3825017-showed the highest risk for hyperuricaemia with an OR of 92.23 (p=9.55×10(-3)).
|
26603249 |
2015 |
|
rs475688
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The aim of this study is to explore whether the polymorphisms of rs475688 and rs3825016 in the solute carrier family 22 member 12 (SLC22A12) gene are associated with the susceptibility to gout or hyperuricaemia.
|
29352852 |
2018 |
|
rs505802
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The strongest association was detected at SLC22A12 rs505802 for uric acid (p=2.4×10(-50)) and ABCG2 rs2231142 for hyperuricemia (p3.6×10(-10)).
|
23238572 |
2013 |
|
rs559946
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our study suggests that the rs559946 polymorphism is associated with increased HUA risk and may also contribute to gout development in Han Chinese men.
|
23981340 |
2014 |
|
rs75786299
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Individuals carrying the GATAG haplotype (n=32)-a relatively common variant consisting of rs7929627, rs75786299 and rs3825017-showed the highest risk for hyperuricaemia with an OR of 92.23 (p=9.55×10(-3)).
|
26603249 |
2015 |